Metformin, one of the most prescribed medicines for type 2 diabetes, may do more than control sugar. A new study in BMJ Open Diabetes Research & Care found that long-term use of metformin can reduce copper and iron levels while increasing zinc in the blood.
What the study found
In people taking metformin:
- Copper levels decreased
- Iron levels decreased
- Zinc levels increased
- Vitamin B12 levels decreased
- Homocysteine levels increased
Why this matters
Metformin is believed to bind with metals, especially copper. This may partly explain its wide benefits in diabetes management beyond lowering sugar. But reduced copper and iron could also mean risk of deficiencies if not monitored.
Should patients worry?
Doctors say this is not a reason to stop metformin. The findings are early and need more research.
- The most important advice remains: check Vitamin B12 regularly if you are on metformin for years.
- Do not take copper, iron, or zinc supplements without medical advice.
Also read-Diabetes Type 2 Ko Reverse Karne Mein Ayurveda Kitna Effective Hai?
Bottom line
Metformin users may have 10% less copper, 6% less iron, and 6% more zinc in their blood compared to non-users. Along with the well-known drop in Vitamin B12, this could be another clue to how the drug works in the body. For now, patients should continue treatment but stay alert to regular health checkups.
